Home Knowledge base The Role of Red Blood Cells in Blood Types: Understanding Your Blood Group

The Role of Red Blood Cells in Blood Types: Understanding Your Blood Group

Immunology plays an important role in understanding blood types and red blood cells, which are crucial for transfusions. Every person in the world has a blood type, determined by the combination of genes inherited from their parents: A, B, or O. If your father gives you blood type A and your mother gives you blood type B, then blood type AB is formed. Knowing your blood type is crucial for determining who can donate red blood cells to you and who you can donate to. Certain blood types are in higher demand than others, making understanding your blood type essential in the field of immunology.

In the UK, there are eight main blood types: A, B, AB and O, each with either Rh positive or negative. Blood type O is the most common, followed by A. The NHS Blood and Transplant organization encourages people to become blood donors to help those in need.

What is blood type?

Blood type is a vital component of immunology. Blood types are structures made up of proteins or sugars found on the surface of red blood cells. These structures differ among individuals and are classified according to Dr. Karl Landsteiner's ABO system, which was developed in 1900. Your blood type is determined by the sugar structure on the surface of your red blood cells. Blood type A is identified by one structure, while blood type B is identified by a different structure. If your red blood cells contain both sugar structures, you have blood type AB, and if they don't have any sugar structures, you have blood type O.

Rh factor

If you need a blood transfusion, another blood type is very important. Namely the Rhesus D blood group. This is also called the Rh factor. If the Rhesus D blood group is on the edge of your red blood cells, then you are Rh positive (RhD positive). If this blood group is absent from the edge of your red blood cells, you are Rh negative (RhD negative).

If your blood does not contain sugar structures but does contain the Rh factor, you are O positive (O+). If your blood contains the sugar structures of blood type A but not the Rh factor, you are A negative (A-).

The Rh factor is also determined by heredity. You receive a positive Rh factor (+) or a negative Rh factor (-) from both parents. If one parent gives a positive Rh factor (+) and the other gives a negative (-), the child automatically has a positive Rh factor (+).

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